The Fluoride and Trace Metals Contents in the Rift Valley Lake Eyasi Salt a Possible Threat to Human Health
DOI:
https://doi.org/10.61538/huria.v24i3.372Abstract
The objective of the present investigation was to determine the actual concentrations of both fluoride and trace metals in Lake Eyasi salts and later to decide whether the salt is safe for human consumption. The importance of knowing optimum concentration of both fluoride and trace metals in human meals cannot be overemphasized, however, if it is left to exceed a minimum set by WHO may be detrimental to human health in both short and long term. This paper has revealed that lake brines and salt crusts contain fluoride concentration with mean values of 273 mg.dm-3F- and 2.30 g.Kg-1F-, respectively of which are above the acceptable values. In addition, lead content in lake brines is up to 1.83 mg.dm-3 Pb; Cd = 1.40 mg.dm-3; Mn = 0.46 mg.dm-3, and iron is up to 6.60 mg.dm-3 Fe, thus exceeding WHO and Tanzanian limits which are 0.10 mg.dm-3 Pb and 0.10 to 1.00 mg.dm-3  Fe, respectively. In fact silicon is another contaminant noted in the salt crust which is up to 72.40 g.Kg-1. It is imperative for Lake Eyasi salts to undergo a thorough purification to remove all contaminants found and stop population from using impure salts which might have long term health problems (ageing, fluorosis, thyroid gland, hypothyroidism, neurological complications, urinary stone deposition of iron oxide and inflammations).References
American Public Health Association Standard Method for the Examination of Water and Wastewater 3rd ed. (1971). Washington.
ATSDR, Draft Toxicological Profile for Lead, US Department of Health and Human Services. (2005). Atlanta, Georgia, USA.
Badet, C. and Richard, Y. (2004). EMC-Dent. 1 (1), 40-48.
Baker, B. H., Mohr, P. A. and Williams, L. A. J. (1983). Geology of the Eastern Rift System of Africa. Geol. Soc. Amer. Special Paper, 136, 1-67.
Barier, O., Arreola-Mendoza, L. and Dal Rozo, L. (2010). “Molecular
Mechanisms of Fluoride Toxicocity†Chemical Biological
Interactions, 188 (2), 319-333.
Cady, G. H. and Misra, S. (1974). Hydrolysis of Sulfurly Fluoride,
Inorganic Chemistry, 13 (4), 837-841.
Chimlea, C. M. W. (2007). “Silica a Mineral of Unknown but
Emerging Health Importance,†Journal of Nutrition Health and Aging, 11 (2), 93-110.
Collip, P. J., Chen, S.T., Maitinsky, S. (1983). Manganese in Infant Formulas and Learning Disability,†Ann. Nutr. Metab. 27 (6), 488-494.
Condelaria, M., Garcis-Arias, A., Cetian, L. and Duenas-Gonzalez, A. (2006). Radio Sensitizers in Cervical Cancer: Cisplatin and
Beyond,†Radiat Oncol., 1 (1), 15-32.
Czajka, M. (2012). “Systemic Effects of Fluoridation,†Journal of
Orthomolecular Medicine, 27 (3), 123-130.
Dar es salaam Water Supply Corporation-Water Quality Laboratory, (1989). Annual Report.
Deboral, S. Lake Manyara National Park, (1980). Elsevier Scientific Publishing Co. Amsterdam.
Dean, E. and Elvove, E. (1937). Further Studies on the Minimum Threshold of Chronic Endemic Dental Fluorosis, Public Health Reports, 52, 1249-1264.
Elot, P., Ahaulcour, F. and Tjalma, W. (2007). Management of Recurrent Cervical cancer, Eur. J. Gynaecol. Concol., 28 (5), 435-441.
European Commission Critical, “Review of Any New Evidence on the Hazards Profile, Heath Effects and Human Exposure to Fluoride and Fluoridating Agents of Drinking water,†(2011). Scientific Committee on Health and Environmental Risks (SCHER).
Evans, J. D., Rugg-Gunn, J. A. and Tabari, D, E. (1995). “The Effects of 25 years of Water Fluoridation in Newcastle Assessed in Four Surveys of 5-Year-old Children Overan18-Years Period,
Br. Dent. J., 178 (2), 60-64.
Fisher, L. R., Medcalf, W. T. and Henderson, C. M. (1989). “Endemic Fluorosis with Spinal Cord Compression. A Case Report and
Review†Archives of Internal Medicine, 149 (3), 697-700.
Frant, M. S. and Ross, J. W. Jr. (1966). Electrode for Sensing Fluoride Ion Activity in Solution. Science, 154 (3756), 1553-1555.
Gamakaranage, C., Rodrigo, C., Wearasinghe, S. Gnanathasan, V. P. and Fernando, H.(2011). Complications and Management of Acute Copper Sulphate Poisoning; A Case Discussion, J. Occup.
Med. Toxicol., 6 (1), 34-38.
Gonzalez-Cortijo, L. and Corballo, N. (2008). Novel Chemotherapy
Approaches in Chemoradiation Protocal. Gyneco. Oncol., 110
(3), 45-48.
Gunter, T. E., Gerstner, B. and Gunter, K. K. et al. (2013). “Manganese Transport Via the Transferring Mechanism,†Neurotoxicology, 34 (1), 118-127.
Hamilton, R. I. Biochemical Effects of Fluoride on Oral Bacteria, (2004). Journal of Dental Research, 69 (5), 660-667.
Hollemen, A. F. and Wiberg, E. (2001). “Inorganic Chemistry†Academic Press: San Diego.
Instruction Model 2380 Atomic Absorption Spectrophotometer,
(1984). The Perkin–Elmer New York.
Iwami, R. I., Hata, S., Schachtele, F. C. and Yamada, Y. (1995). “Simultaneous Monitoring of Intracellular pH and Proton
Excretion During Glycolysis by Steptococcus Mutants and Streptococcus Sanguis: Effect of Low pH and Fluoride†Oral Microbiology and Immunology, 10 (6), 355-359.
Jadia, D. C. and Fulebar, H. M. (2009). Phytoremediation of Heavy Metals: Recent Techniques,â€Africa Journal of Biotechnology, 8 (6), 921-928.
Judd, F. G. (1997). Good Teeth: Birth to Death-Prescription for Perfect Teeth, Research Publications. Co., Glendale, Calif. USA.
Kaosar, A., Kazuki, S., Sotashi, I. and Hiroshi, H. (2004). Reducing Effect of Ingesting Tannic Acid on the Absorption of Iron, But not of Zinc, Copper, and Manganese by Rats, Bioscience
Biotechnology and Biochemistry and Agrochemistry, 68 (3), 584-592.
Kayngo, H. and Julson, L. J. (2008). Effects of High Levels of Dietary
Silicon on Bone Development of Growing Rats and Turkeys, Fed semi-purified Diet,†Biological Trace Element Research, 123 (3), 191-201.
Lingane, J. J. (1967). “A Study of the Lanthanum Fluoride Membrane Electrode for End Point Detection in Titration of Fluoride with Thorium, Lanthanum, and Calcium,†J. Anal. Chem. 39 (1), 881889.
Long, Y. G., Wang, Y. N., Chen, J., Jiang, S. F. Nordberg, A. and Guan, Z. Z. (2002). Chronic Fluoride Toxicity Decreases the Number of Nicotinic Acetylcholine Receptor in Rat Brain,â€
Neurotoxicol. Teratol., 24 (6), 751-757.
Luis, A., May-Ix, J., Abriel, R., Martha, M., Arturo, F., Castellanos, R., Chel, G., Madaan, N. and Mudgal, V. (2009). “Differential
Tolerance Behaviour of Safflower Accessions to Some Heavy
Metals,†Int. J. Apply. Environ. Sci., 4 (4), 413-420.
Mahaffey, K. R. (1990). “Environmental Lead Toxicity Nutrition as a
Component of Intervention,†Enviro. Heath Perspect, 89, 75-78.
Mudgal, U., Madaan, N., and Mudgal, A. (2010). “Heavy Metals in Plant: Phytoremediation: Plant Used to Remediate Heavy
Metal Pollution,†Agric. Biol., J., 1 (2), 40-46.
Nagajyoti, C. P. and Lee, D. K. (2010). Heavy Metals Occurrence and Toxicity for Plants: A Review. Environmental Chemistry Letters, 8 (3), 199-216.
National Health and Medical Research Council Public Statement: The Efficacy of Fluoridation, (2007). NHMRC, Canberra.
National Institute for Dental and Craniofacial Research, (2011). The Story of Fluoridation, NIDCR Bethesda, Md, USA.
Nielssen, H. F. and Sandstead, H. H. (1974). Are Nickel, Vanadium, Silicon, Fluoride and Tin, Essential for Man? A Review†Journal of Clinical Nutrition, 27 (5), 515-520.
Nissenbaum, A. (1980). Hypersaline Brines and Evaporitic Environments; Elsevier Scientific Publishing Co., New York.
Okazaki, K. (1987). “Mg2+F- Interactions During Hydroxyapatite
Formation,†Magnesium, 6 (6), 296-301.
Onyango, S. M., Kojima, Y., Aoyi, O., Bernardo, E. C. and Matsuda,
H. (2004). Adsorption Equilibrium and Solution Chemistry
Dependence of Fluoride Removal From Water by Trivalent-
Cation Exchanged Zeolete F-9. J. Colloidal Interface Sci., 279 (2), 341-350.
Palacios, C. (2006). The Role of Nutrients in Bones Heath from A to
Z. Crit. Rev. Food Sci. Nutr., 46 (8), 621-628.
Pattel, B. D., Welch, A. A. and Wareham, N. J. (2006). “Dietary Antioxidants and Asthma in Adults,†Thorax, 61 (5), 388-393.
Peteson, R. C. (2011). “Clinical Practice Mild Cognitive Impairment.
N,†Engl. J. Med., 364 (23), 2227-2234.
Pettifor, M. T., Schnitzler, M. C., Ross, P. F. and Moodley, G. G. (1989). “Endemic Skeletal Fluorosis in Children: Hypocalcemia and the Presence of Prenatal Resistance of Parathyroid
Hormone,†Bone Miner., 7, 275-288.
Pizzo, G., Piscopo, M. R., Pizzo, I. and Giuliana, G. (2007). “Community Water Fluoridation and Caries Prevention: A
Critical Review,†Clinical Oral Investigations, 11 (3), 189-193.
Querfurth, H. W. and Laferla, F. M. (2010). “Alzheimers Disease,†N.
Engl. J. Med., 362 (4), 329-344.
Qulwi, Q. (1995). A Study of Hydrochemistry of Brines and Associated Inflows of Lake Manyara Tanzania. Thesis, University of Dar es Salaam.
Raskin, I. and Ensley, D. B. (2000). “Phytoremediation of Toxic Metals: Using Plants to Clean up the Environment,†John Wiley & Sons, New York, NY, USA.
Reynolds, M. Peterson, E., Quierryn, G., Zhitkovich, A. (2004). “Human Nucleotide Excision Repair Efficiently Removes Chromium-DNA Phosphate Adducts and Protects Cells Against Chromate Toxicity,†J. Biol. Chem., 279 (29), 3041930424.
Saemundsson, K. (2010). East Africa Rift System an Overview. Presented at Short Course
V on Exploration for Geothermal Resources Organized by UNUGTP, GTP and KenGen, at Lake Bogoria and Lake Naivasha, Kenya.
Seabrn, D. C. and Nielsen, H. F. (2002). Dietary Silicon and Arginene Effect Mineral Element Composition of Rat Femur and
Vertebra,†Biological Trace Element Research, 89 (3), 239-250.
Singh, P. P. Barjatiya, M. K. Dhing, S., Bhatnagar, R., Kothari, S. and Dhar, V. (2001). Evidence Suggesting that High Intake of Fluoride Provokes Nephrolithiasis in Tribal Populations,†Urol Res., 29 (4), 238-244.
Singh, R., Gautam, N., Mishra, A. and Gupta, R. (2011). Heavy
Metals and Living Systems: An Overview, India J. Pharmacol., 43 (3), 246-253.
Skoog, D. A. and West, D. M. (2006). Fundamentals of Analytical Chemistry, 6th ed., Holt-Sounders International Editions Japan.
Son, E. W., Lee, S. R., Koo, H. J. et al. (2007). Effects of Supplementation with Higher Levels of Manganese on Immune
Function. Arch. Pharmo. Res., 92 (2), 123-129.
Sunilson, J. A. J., Rejitha, G. and Anandarajagopal, K. et al. (2009). “Cytotoxic Effect of Caytatia Carnosa Leaves on Human Breast
Cancer Cell Lines,†Int. J. Cancer Res., 5, 1-7.
Tandon, S. K., Chatterjee, M., Bhargava, A, Shukla, V. and Bihari, V. (2001). “Lead Poisoning in India Silver Refineries,†Sci. Total Environ., 281 (1-3), 177-182.
Teotia, M., Teotia, S. P. S. and Singh, P. K. (1998). “Endemic Chronic
Fluoride Toxicity and Dietary Calcium Deficiency Interaction Syndromes of Metabolic Bone Disease and Deformities in
India,†India Journal of Pediatrics, 65 (3), 371-381.
Tokalioglu, S., Kartal, S., Sahin, U. and Turk, J. (2004). Turk J. Chem., 28 (2), 203-211.
Umanzor, J. and Aguiluz, M. (2006). Cisplatin/Gemcitabine Chemotherapy Along with Radiorherapy in Locally Advanced Cervical Carcinoma: A Phase II Trial. Gynecol. Oncol., 100 (1), 70-75.
United State Environmental Protection Agency, Fluoride Report to Congress Section 112 (n) (16), (2000). Clean Air Act, Washington, DC, USA.
Wong, M. H., Fung, F. K. and Carr, P. H. (2003). “ Aluminium and Fluoride Contents of Tea, with Emphasis on Brick Tea and their
Health Implications Review†Toxicology Letters, 137 (12), 111-120.
Wood, R. B. and Talling, J. F. (1988). “Chemical and Algal Relationships in a Salinity Series of Ethiopian Inland Waters,â€
Hydrobiol., 158 (1), 29-67.
Zinabu, M. G. and Pears, N. J. G. (2003). “Concentration of Heavy Metals and Related Trace Elements in Some Ethiopian Riftvalley Lakes and Their In-flows,†Hydrobiologia, 492 (1), 171-178.
Zheng, W., Fus, X. and Dydak, K. et al. (2011). “Biomarkers of Manganese Intoxication. Neurotoxicology, 32 (1), 1-8.
